Four years have passed since the events of *No Way Home*. Peter has grown up and lives in complete solitude, having voluntarily erased himself from the memories of those he loves. Continuing to fight crime in a New York City that no longer knows his name, he has devoted himself entirely to protecting the city. But as his workload grows, the pressure on him only intensifies, causing an unexpected physical transformation that threatens his very existence. At the same time, a strange new wave of crime leads to the emergence of one of the most powerful enemies he has ever faced.